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All therapeutic applications remain investigational, and long-term human safety data are absent from the published literature

While glutathione is widely known for protecting cells from damage, the team found that cancer cells can hijack it and use it as a nutrient, particularly in environments where other resources are scarce

Bacterial challenges generally induced multiple GSTs, however individual members of the GST family were specifically modified depending upon the virulence of bacterial strains and the outcome of interaction

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Ferroptotic pores induce Ca(2+) fluxes and ESCRT-III activation to modulate cell death kinetics